Ramesh Ponnuru (; born August 16, 1974) is an American conservative thinker, political pundit, and journalist. He is a senior fellow at the American Enterprise Institute since 2012. He is the editor of National Review magazine, a contributing columnist for The Washington Post, and a contributing editor to the domestic policy journal National Affairs.

Ponnuru has written on a wide array of political and policy topics, appeared on numerous public affairs and news interview programs, reflecting his widely respected voice on conservative policy. In 2015, Politico Magazine listed both him and his wife, April Ponnuru, as two of the top "Politico 50" influential leaders in American politics. This was the first and only time that a husband and wife appeared on the list at the same time.